Subacute Combined Degeneration with Motor Neuropathy Following Nitrous Oxide Abuse

The neurotoxicity of nitrous oxide (N<sub>2</sub>O) is known to be mainly occurred by interference with action vitamin B12. A 38-year-old male presented progressive gait instability after recreational inhalational use N<sub>2</sub>O for 2 months. Although spine magnetic resonance image showed typical subacute combined degeneration, nerve conduction study motor neuropathy that atypical findings B12 deficiency. This case suggests N<sub>2</sub>O-induced can develop separately from a